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Immunodeficient mice (NIVO)


NIVO are useful for oncology, immunology, infectious disease, stem cell studies and other research. As the diversity and specialized research fields increase, choosing the most appropriate mouse models is important for your valuable research. Our animal models have been used for research conducted at national research institutes, organizations and industry.



NIVO mice are deficient in mature T, B, and NK cells. and are a key carrier for humanized mice, xenografts and immune reconstitution. The NIVO  immunodeficient mice is genetically modified using CRISPR/Cas9 technique to knock out Prkdc and IL2rg genes from NOD mice.

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